Rink Amide AM Resin (200–400 mesh) is a widely utilized solid-phase support in peptide synthesis, particularly for generating C-terminal peptide amides using Fmoc-based solid-phase peptide synthesis (SPPS). Its design facilitates efficient synt
hesis and straightforward cleavage, making it a staple in both research and industrial peptide production.
Key Features
Resin Type: Polystyrene cross-linked with 1% divinylbenzene (DVB)
Functional Group: Rink amide linker attached via norleucine to aminomethylpolystyrene
Mesh Size: 200–400 mesh
Loading Capacity: Varies by supplier, typically ranging from 0.3 to 1.2 mmol/g
Appearance: White to pale yellow beads
Swelling Volume: Lot-specific; generally ≥5 mL/g in solvents like DMF or CH₂Cl₂
Storage Conditions: Store at 2–30 °C in a dry environmentMilliporeSigma+1MilliporeSigma+1MilliporeSigma+1cblpatras.gr+1Chem-Impex
Applications
Rink Amide AM resin is particularly suited for:
Fmoc-Based SPPS: Facilitates the synthesis of peptides with C-terminal amides, which are prevalent in bioactive peptides and therapeutic agents.
Peptide Library Construction: Supports the generation of diverse peptide sequences for screening and research purposes.
Bioconjugation: Enables the attachment of peptides to other biomolecules, aiding in the development of targeted drug delivery systems.Chem-Impex+1Chem-Impex+1
Technical Specifications
Polymer Matrix: Polystyrene cross-linked with 1% DVB
Functional Group: Rink amide linker
Loading Capacity: Typically between 0.3 and 1.2 mmol/g, depending on the supplier
Mesh Size: 200–400 mesh
Swelling Volume: Lot-specific; generally ≥5 mL/g in solvents like DMF or CH₂Cl₂
Storage Conditions: Store at 2–30 °C in a dry environmentChemPep+9MilliporeSigma+9MilliporeSigma+9CymitQuimica+1shop.bachem.com+1
Availability & Pricing
Rink Amide AM resin is available from various suppliers in different quantities. For instance:shop.bachem.com
Chem-Impex offers 1 g for approximately $45.00 USD.
ChemPep provides 5 g for around $100.00 USD.
Bachem lists 1 g at €71.70.Chem-Impex+1Chem-Impex+1ChemPepshop.bachem.com+1CymitQuimica+1
Prices may vary based on supplier and region. For the most accurate and up-to-date pricing, it's recommended to consult authorized distributors or the manufacturer's website.
Documentation & Safety
Safety Classification: Not classified as hazardous under standard regulations.
Handling Precautions: As with all chemical reagents, appropriate safety measures should be taken, including the use of personal protective equipment (PPE) and working in a well-ventilated area.
Phone : +49 1512 4714765 ( Germany )
Phone : +1 (702) 381-3042 ( USA )
Email : [email protected]
Address : Cunostraße 56, 14193 Berlin. Germany
Address : 7373 Rowlett Park Dr, Tampa, FL 33610, United States.